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Tanabe adipor2 protein
Adipor2 Protein, supplied by Tanabe, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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Tanabe adipor2 protein
Adipor2 Protein, supplied by Tanabe, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cusabio adipor2 protein expression
Fig. 4 | <t>AdipoR2</t> deficiency abolishes the protective effect of SCM-198 on ALF models. a Representative photograph of WT and Adipor2-/- mouse livers (48 hpi). SCM-198 was given at 24 hpi (in a–f). Black arrowheads indicate sites of severe lesions. Scale bars, 5 mm. b HE staining and quantification analysis on WT and Adipor2-/- mouse liver sections, 48 hpi. Scale bars, 100 μm. c Serum levels of ALT and AST, measured at 48 hpi in WT and Adipor2-/- TAA/APAP-intoxicated mice. d Quantification of GSH in liver tissues of WT and Adipor2-/- mice, 48 hpi.
Adipor2 Protein Expression, supplied by Cusabio, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Human Protein Atlas adipor2 protein expression
Fig. 4 | <t>AdipoR2</t> deficiency abolishes the protective effect of SCM-198 on ALF models. a Representative photograph of WT and Adipor2-/- mouse livers (48 hpi). SCM-198 was given at 24 hpi (in a–f). Black arrowheads indicate sites of severe lesions. Scale bars, 5 mm. b HE staining and quantification analysis on WT and Adipor2-/- mouse liver sections, 48 hpi. Scale bars, 100 μm. c Serum levels of ALT and AST, measured at 48 hpi in WT and Adipor2-/- TAA/APAP-intoxicated mice. d Quantification of GSH in liver tissues of WT and Adipor2-/- mice, 48 hpi.
Adipor2 Protein Expression, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Santa Cruz Biotechnology kda santa cruz biotechnology mttp microsomal triglyceride transfer protein 97 kda santa cruz biotechnology adipor2 adiponectin receptor
Fig. 4 | <t>AdipoR2</t> deficiency abolishes the protective effect of SCM-198 on ALF models. a Representative photograph of WT and Adipor2-/- mouse livers (48 hpi). SCM-198 was given at 24 hpi (in a–f). Black arrowheads indicate sites of severe lesions. Scale bars, 5 mm. b HE staining and quantification analysis on WT and Adipor2-/- mouse liver sections, 48 hpi. Scale bars, 100 μm. c Serum levels of ALT and AST, measured at 48 hpi in WT and Adipor2-/- TAA/APAP-intoxicated mice. d Quantification of GSH in liver tissues of WT and Adipor2-/- mice, 48 hpi.
Kda Santa Cruz Biotechnology Mttp Microsomal Triglyceride Transfer Protein 97 Kda Santa Cruz Biotechnology Adipor2 Adiponectin Receptor, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Alpha Diagnostics adipor2 protein
Fig. 4 | <t>AdipoR2</t> deficiency abolishes the protective effect of SCM-198 on ALF models. a Representative photograph of WT and Adipor2-/- mouse livers (48 hpi). SCM-198 was given at 24 hpi (in a–f). Black arrowheads indicate sites of severe lesions. Scale bars, 5 mm. b HE staining and quantification analysis on WT and Adipor2-/- mouse liver sections, 48 hpi. Scale bars, 100 μm. c Serum levels of ALT and AST, measured at 48 hpi in WT and Adipor2-/- TAA/APAP-intoxicated mice. d Quantification of GSH in liver tissues of WT and Adipor2-/- mice, 48 hpi.
Adipor2 Protein, supplied by Alpha Diagnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Fig. 4 | AdipoR2 deficiency abolishes the protective effect of SCM-198 on ALF models. a Representative photograph of WT and Adipor2-/- mouse livers (48 hpi). SCM-198 was given at 24 hpi (in a–f). Black arrowheads indicate sites of severe lesions. Scale bars, 5 mm. b HE staining and quantification analysis on WT and Adipor2-/- mouse liver sections, 48 hpi. Scale bars, 100 μm. c Serum levels of ALT and AST, measured at 48 hpi in WT and Adipor2-/- TAA/APAP-intoxicated mice. d Quantification of GSH in liver tissues of WT and Adipor2-/- mice, 48 hpi.

Journal: Nature communications

Article Title: Selectively targeting the AdipoR2-CaM-CaMKII-NOS3 axis by SCM-198 as a rapid-acting therapy for advanced acute liver failure.

doi: 10.1038/s41467-024-55295-7

Figure Lengend Snippet: Fig. 4 | AdipoR2 deficiency abolishes the protective effect of SCM-198 on ALF models. a Representative photograph of WT and Adipor2-/- mouse livers (48 hpi). SCM-198 was given at 24 hpi (in a–f). Black arrowheads indicate sites of severe lesions. Scale bars, 5 mm. b HE staining and quantification analysis on WT and Adipor2-/- mouse liver sections, 48 hpi. Scale bars, 100 μm. c Serum levels of ALT and AST, measured at 48 hpi in WT and Adipor2-/- TAA/APAP-intoxicated mice. d Quantification of GSH in liver tissues of WT and Adipor2-/- mice, 48 hpi.

Article Snippet: ADIPOR2 protein expression and purification His-tagged ADIPOR2 was expressed in suspension HEK293T cells by Cusabio (Wuhan, China).

Techniques: Staining

Fig. 5 | SCM-198 regulates NO production through NOS3. a Detection of NO with DAF-FM DA (green) in control or SCM-198 treated AML12 cells. Scale bar, 20 µm. b NO content of the AML12 cells transfected with Adipor2 siRNA or negative control siRNA. Cells were treated with DMSO or SCM-198 for 24 h after H2O2 exposure. c NO content of the TAA/APAP-induced ALF mouse liver tissues measured at 48 hpi. Injured mice were treated with saline or SCM-198 at 24 hpi (in c, d, f, g, i–r). d NO content of WT and Adipor2-/- liver tissues, after TAA/APAP-induced ALF, measured at 48 hpi, normalized to the saline-treated group. e NO content of AML12 cells, with or without L-NAME. f Quantification of necrosis on liver sections of WT and Nos3-/-

Journal: Nature communications

Article Title: Selectively targeting the AdipoR2-CaM-CaMKII-NOS3 axis by SCM-198 as a rapid-acting therapy for advanced acute liver failure.

doi: 10.1038/s41467-024-55295-7

Figure Lengend Snippet: Fig. 5 | SCM-198 regulates NO production through NOS3. a Detection of NO with DAF-FM DA (green) in control or SCM-198 treated AML12 cells. Scale bar, 20 µm. b NO content of the AML12 cells transfected with Adipor2 siRNA or negative control siRNA. Cells were treated with DMSO or SCM-198 for 24 h after H2O2 exposure. c NO content of the TAA/APAP-induced ALF mouse liver tissues measured at 48 hpi. Injured mice were treated with saline or SCM-198 at 24 hpi (in c, d, f, g, i–r). d NO content of WT and Adipor2-/- liver tissues, after TAA/APAP-induced ALF, measured at 48 hpi, normalized to the saline-treated group. e NO content of AML12 cells, with or without L-NAME. f Quantification of necrosis on liver sections of WT and Nos3-/-

Article Snippet: ADIPOR2 protein expression and purification His-tagged ADIPOR2 was expressed in suspension HEK293T cells by Cusabio (Wuhan, China).

Techniques: Control, Transfection, Negative Control, Saline